# Analysis of Physiological Systems: The White-Noise Approach by Panos Z. Marmarelis M.D., Ph.D., Vasilis Z. Marmarelis

By Panos Z. Marmarelis M.D., Ph.D., Vasilis Z. Marmarelis (auth.)

In learning physiological platforms bioscientists are constantly confronted with the matter of offering descriptions of cause-effect relationships. This job is generally conducted throughout the functionality of stimulus-response experiments. some time past, the layout of such experiments has been advert hoc, incomplete, and positively inefficient. Worse but, bioscientists have did not make the most of advances in fields at once concerning their difficulties (specifically, advances within the zone of platforms analysis). The raison d'etre of this ebook is to rectify this deficiency through delivering the physiologist with methodological instruments that may be invaluable to her or him in daily labora tory encounters with physiological structures. The e-book was once written in order that it might be useful, necessary, and up-to date. With this in brain, components of it provide step by step descriptions of within the laboratory. it's was hoping that this systematic methods to be increases the usefulness of the ebook to the common learn physiologist and, probably, decrease the necessity for in-depth wisdom of a few of the linked arithmetic. although the cloth bargains with state-of-the paintings concepts in platforms and sign research, the mathematical point has been stored low for you to be understandable to the typical physiologist without large education in arithmetic. To this finish, mathematical rigor is frequently sacrificed without problems to intuitive uncomplicated arguments.

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If the ensemble is weakly stationary-then it is also strongly stationary since all the higher-order correlations (moments) are completely specified by the first two, which are time invariant. In general, to specify completely an arbitrary distribution, we need to know all of its moments. This is easily shown. )2 p(X) l+iwx+--,-+" 2. (iW)2 . )n '+--,-+'" r n. = 1+ iWI1-1 +-2' 11-2 + ... +-,-l1-n + ... n. 104) The term-by-term integration holds if the moments are finite and the series converges absolutely near W = O.

3. Power Spectrum As discussed previously, we describe and analyze random signals by measuring certain statistical quantities, either on the ensemble or a particular sample. Such statistical quantities include the moments of the signal (underlying amplitude probability distribution) and correlation functions. It is desirable, however, to have a description of a stochastic signal in the frequency domain, in much the same way that the Fourier series and Fourier transform serve for periodic and transient signals.

This is only true for a linear system. Now, let us consider an input x(t) that is ideal white noise. The ideal white noise is a stationary random process, which has the fundamental JL Fig. 6. Response of RC circuit to impulse. 23 Analysis of Physiological Signals property that any two samples of it are statistically independent. It also has a zero average value. 43) = POeT) where the function 0 (T ) (delta function) is defined as being zero whenever T -:jo 0 and as having an integral of lover any interval that includes the origin.